The ensemble allostery model (EAM) can be used to predict proteins that are resistant to drug resistance.Read More
Protein misfolding plays a significant role in neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's.Read More
Are you wondering why the medicine is not working for your disease?Read More
Gain Therapeutics is working on these factors to design the most easily binding drugs.Read More
These concepts are illustrated here with the specific case of the human glucocorticoid receptor, a medically important multi-domain allosteric protein that contains Read More
If it is possible to unfold the inactive state, it can reduce binding incompetence arising from folding or conformational dynamics. Thus, the Read More
The allosteric effect is an important mechanism of regulation in the biological process that binds the ligand on one side of the Read More
Prion disease, which is also known as transmissible spongiform encephalopathies or TSEs are a rare group of neurodegenerative disorders affecting both mammals Read More